![Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis | PNAS Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis | PNAS](https://www.pnas.org/cms/10.1073/pnas.2122287119/asset/f91ab14e-cb64-4f8e-902e-ae6a9604ae76/assets/images/large/pnas.2122287119fig01.jpg)
Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis | PNAS
![IJMS | Free Full-Text | Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport IJMS | Free Full-Text | Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport](https://pub.mdpi-res.com/ijms/ijms-23-01264/article_deploy/html/images/ijms-23-01264-g001.png?1642937775)
IJMS | Free Full-Text | Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport
![Biomedicines | Free Full-Text | Effects of a Combination of Empagliflozin Plus Metformin vs. Metformin Monotherapy on NAFLD Progression in Type 2 Diabetes: The IMAGIN Pilot Study Biomedicines | Free Full-Text | Effects of a Combination of Empagliflozin Plus Metformin vs. Metformin Monotherapy on NAFLD Progression in Type 2 Diabetes: The IMAGIN Pilot Study](https://www.mdpi.com/biomedicines/biomedicines-11-00322/article_deploy/html/images/biomedicines-11-00322-g001-550.jpg)
Biomedicines | Free Full-Text | Effects of a Combination of Empagliflozin Plus Metformin vs. Metformin Monotherapy on NAFLD Progression in Type 2 Diabetes: The IMAGIN Pilot Study
![Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney | Scientific Reports Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fsrep35952/MediaObjects/41598_2016_Article_BFsrep35952_Fig1_HTML.jpg)
Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney | Scientific Reports
![IJMS | Free Full-Text | Metformin Reduces Potassium Currents and Prolongs Repolarization in Non-Diabetic Heart IJMS | Free Full-Text | Metformin Reduces Potassium Currents and Prolongs Repolarization in Non-Diabetic Heart](https://pub.mdpi-res.com/ijms/ijms-23-06021/article_deploy/html/images/ijms-23-06021-g001.png?1653640587)
IJMS | Free Full-Text | Metformin Reduces Potassium Currents and Prolongs Repolarization in Non-Diabetic Heart
![Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase | Nature Medicine Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase | Nature Medicine](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41591-018-0159-7/MediaObjects/41591_2018_159_Fig1_HTML.png)
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase | Nature Medicine
![Biomolecules | Free Full-Text | Action Mechanism of Metformin and Its Application in Hematological Malignancy Treatments: A Review Biomolecules | Free Full-Text | Action Mechanism of Metformin and Its Application in Hematological Malignancy Treatments: A Review](https://www.mdpi.com/biomolecules/biomolecules-13-00250/article_deploy/html/images/biomolecules-13-00250-g001-550.jpg)
Biomolecules | Free Full-Text | Action Mechanism of Metformin and Its Application in Hematological Malignancy Treatments: A Review
![Pharmaceutics | Free Full-Text | Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs) Pharmaceutics | Free Full-Text | Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)](https://www.mdpi.com/pharmaceutics/pharmaceutics-15-01357/article_deploy/html/images/pharmaceutics-15-01357-g001.png)
Pharmaceutics | Free Full-Text | Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)
![IJMS | Free Full-Text | Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area IJMS | Free Full-Text | Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area](https://pub.mdpi-res.com/ijms/ijms-22-13068/article_deploy/html/images/ijms-22-13068-ag.png?1638781463)
IJMS | Free Full-Text | Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area
![Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next? | ACS Pharmacology & Translational Science Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next? | ACS Pharmacology & Translational Science](https://pubs.acs.org/cms/10.1021/acsptsci.1c00167/asset/images/large/pt1c00167_0007.jpeg)
Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next? | ACS Pharmacology & Translational Science
![Metformin can decrease cartilage degradation in a destabilization of... | Download Scientific Diagram Metformin can decrease cartilage degradation in a destabilization of... | Download Scientific Diagram](https://www.researchgate.net/publication/358486450/figure/fig2/AS:1128855079264277@1646151432750/Metformin-can-decrease-cartilage-degradation-in-a-destabilization-of-the-medial-meniscus.png)
Metformin can decrease cartilage degradation in a destabilization of... | Download Scientific Diagram
![Pharmaceuticals | Free Full-Text | Gastrointestinal Mechanisms Underlying the Cardiovascular Effect of Metformin Pharmaceuticals | Free Full-Text | Gastrointestinal Mechanisms Underlying the Cardiovascular Effect of Metformin](https://pub.mdpi-res.com/pharmaceuticals/pharmaceuticals-13-00410/article_deploy/html/images/pharmaceuticals-13-00410-g001.png?1606037652)
Pharmaceuticals | Free Full-Text | Gastrointestinal Mechanisms Underlying the Cardiovascular Effect of Metformin
![Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes - ScienceDirect Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2589004223001347-fx1.jpg)
Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes - ScienceDirect
![Biomedicines | Free Full-Text | Repurposed Edaravone, Metformin, and Perampanel as a Potential Treatment for Hypoxia–Ischemia Encephalopathy: An In Vitro Study Biomedicines | Free Full-Text | Repurposed Edaravone, Metformin, and Perampanel as a Potential Treatment for Hypoxia–Ischemia Encephalopathy: An In Vitro Study](https://pub.mdpi-res.com/biomedicines/biomedicines-10-03043/article_deploy/html/images/biomedicines-10-03043-g001.png?1669368695)
Biomedicines | Free Full-Text | Repurposed Edaravone, Metformin, and Perampanel as a Potential Treatment for Hypoxia–Ischemia Encephalopathy: An In Vitro Study
![IJMS | Free Full-Text | Metformin Attenuates Slow-to-Fast Fiber Shift and Proteolysis Markers Increase in Rat Soleus after 7 Days of Rat Hindlimb Unloading IJMS | Free Full-Text | Metformin Attenuates Slow-to-Fast Fiber Shift and Proteolysis Markers Increase in Rat Soleus after 7 Days of Rat Hindlimb Unloading](https://pub.mdpi-res.com/ijms/ijms-24-00503/article_deploy/html/images/ijms-24-00503-g001.png?1672307690)
IJMS | Free Full-Text | Metformin Attenuates Slow-to-Fast Fiber Shift and Proteolysis Markers Increase in Rat Soleus after 7 Days of Rat Hindlimb Unloading
![Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight - ScienceDirect Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S155041312300092X-fx1.jpg)
Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight - ScienceDirect
![IJMS | Free Full-Text | Actions of Metformin in the Brain: A New Perspective of Metformin Treatments in Related Neurological Disorders IJMS | Free Full-Text | Actions of Metformin in the Brain: A New Perspective of Metformin Treatments in Related Neurological Disorders](https://www.mdpi.com/ijms/ijms-23-08281/article_deploy/html/images/ijms-23-08281-g001.png)
IJMS | Free Full-Text | Actions of Metformin in the Brain: A New Perspective of Metformin Treatments in Related Neurological Disorders
![Biomedicines | Free Full-Text | Clinical Implication of Metformin in Relation to Diabetes Mellitus and Ovarian Cancer Biomedicines | Free Full-Text | Clinical Implication of Metformin in Relation to Diabetes Mellitus and Ovarian Cancer](https://pub.mdpi-res.com/biomedicines/biomedicines-09-01020/article_deploy/html/images/biomedicines-09-01020-g001.png?1629085275)
Biomedicines | Free Full-Text | Clinical Implication of Metformin in Relation to Diabetes Mellitus and Ovarian Cancer
Metformin Hydrochloride Encapsulation by Alginate Strontium Hydrogel for Cartilage Regeneration by Reliving Cellular Senescence | Biomacromolecules
![Pharmaceuticals | Free Full-Text | Metformin a Potential Pharmacological Strategy in Late Onset Alzheimer's Disease Treatment Pharmaceuticals | Free Full-Text | Metformin a Potential Pharmacological Strategy in Late Onset Alzheimer's Disease Treatment](https://www.mdpi.com/pharmaceuticals/pharmaceuticals-14-00890/article_deploy/html/images/pharmaceuticals-14-00890-g001.png)